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Effect of beta lactam antibiotic use in children on pneumococcal resistance to penicillin: prospective cohort study

Nasrin, Dilruba; Collignon, Peter; Roberts, Leslee; Wilson, Elena Alexandrovna; Pilotto, Louis; Douglas, Robert M


Objective: To examine the relation between use of antibiotics in a cohort of preschool children and nasal carriage of resistant strains of pneumococcus. Design and participants: Prospective cohort study over two years of 461 children aged under 4 years living in Canberra, Australia. Main outcome measures: Use of drugs, respiratory symptoms, and visits to doctors were documented in a daily diary by parents of the children during 25 months of observation. Isolates of pneumococci, which were...[Show more]

CollectionsANU Research Publications
Date published: 2002
Type: Journal article
Source: BMJ - British Medical Journal


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