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Binding site stoichiometry and the effects of phosphorylation on human alpha 1 homomeric glycine receptors

Gentet, Luc; Clements, John D

Description

The kinetic properties of the human α1 homomeric glycine receptor were investigated. Receptors were expressed in HEK 293 cells, and glycine was applied to outside-out membrane patches with submillisecond solution exchange. The activation time course of t

dc.contributor.authorGentet, Luc
dc.contributor.authorClements, John D
dc.date.accessioned2015-12-13T23:40:18Z
dc.date.available2015-12-13T23:40:18Z
dc.identifier.issn0022-3751
dc.identifier.urihttp://hdl.handle.net/1885/94400
dc.description.abstractThe kinetic properties of the human α1 homomeric glycine receptor were investigated. Receptors were expressed in HEK 293 cells, and glycine was applied to outside-out membrane patches with submillisecond solution exchange. The activation time course of t
dc.publisherCambridge University Press
dc.sourceJournal of Physiology
dc.subjectKeywords: glycine; glycine receptor; strychnine; binding kinetics; binding site; cell membrane; concentration (parameters); controlled study; human; human cell; molecular interaction; phosphorylation; priority journal; receptor binding; receptor down regulation; re
dc.titleBinding site stoichiometry and the effects of phosphorylation on human alpha 1 homomeric glycine receptors
dc.typeJournal article
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.citationvolume544
dc.date.issued2002
local.identifier.absfor110902 - Cellular Nervous System
local.identifier.ariespublicationMigratedxPub23984
local.type.statusPublished Version
local.contributor.affiliationGentet, Luc, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationClements, John D, College of Medicine, Biology and Environment, ANU
local.bibliographicCitation.issue1
local.bibliographicCitation.startpage97
local.bibliographicCitation.lastpage106
local.identifier.doi10.1113/jphysiol.2001.015321
dc.date.updated2015-12-12T09:28:40Z
local.identifier.scopusID2-s2.0-0036793188
CollectionsANU Research Publications

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