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A malaria scavenger receptor-like protein essential for parasite development

Claudianos, Charles; Dessens, Johannes T.; Trueman, Holly E.; Mendoza, Jacqui; Arai, Meiji; Butcher, Geoff A.; Crompton, Tessa; Sinden, Roberet E.

Description

Malaria parasites suffer severe losses in the mosquito as they cross the midgut, haemolymph and salivary gland tissues, in part caused by immune responses of the insect. The parasite compensates for these losses by multiplying during the oocyst stage to form the infectious sporozoites. Upon human infection, malaria parasites are again attenuated by sustained immune attack. Here, we report a single copy gene that is highly conserved amongst Plasmodium species that encodes a secreted protein...[Show more]

CollectionsANU Research Publications
Date published: 2002
Type: Journal article
URI: http://hdl.handle.net/1885/94361
Source: Molecular Microbiology
DOI: 10.1046/j.1365-2958.2002.03118.x

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