Structures of Flagranones A, B and C, Cyclohexenoxide antibiotics from the nematode-trapping fungus Duddingtonia flagrans

Abstract

Spectroscopic data define the structures of the flagranones A, B and C from the nematode-trapping fungus Duddingtonia flagrans. These antibiotics are structurally related to the farnesylated cyclohexenoxides of the oligosporon group recently isolated from the nematode-trapping fungus Arthrobotrys oligospora, and show similar antimicrobial activity.