Skip navigation
Skip navigation

Multinucleation and preservation of nuclear integrity of macrophages

Sorimachi, Kenji; Naora, Hiroto; Akimoto, Kazumi; Niwa, Akira

Description

Rat bone marrow-derived macrophages formed multinucleated giant cells spontaneously when cultured in slide glass chambers or when induced with the polyanion acetyl lignin. Nuclei in such cells tended to cluster in distinct rings. DNA fragmentation appeared to occur in multinucleated cells, as detected by 3' end-labeling. Southern blot analyses, using probes specific for nucleolar and non-nucleolar genes, indicated that chromatin DNA was fragmented whereas nucleolar DNA was relatively intact....[Show more]

CollectionsANU Research Publications
Date published: 1999
Type: Journal article
URI: http://hdl.handle.net/1885/93705
Source: Cell Biology International
DOI: 10.1006/cbir.1998.0266

Download

File Description SizeFormat Image
01_Sorimachi_Multinucleation_and_1999.pdf270.74 kBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  12 November 2018/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator