Molecular profiling of behavioural development: differential expression of mRNAs for inositol 1,4,5-trisphosphate 3-kinase isoforms in naive and experienced honeybees (Apis mellifera)
In seeking genetic factors that may control the extended behavioural maturation of adult honeybees we found that inositol 1,4,5-trisphosphate (IP3) 3-kinase, a key enzyme in the IP3-mediated signalling cascade, is differentially expressed in brains of naive, newly emerged bees and experienced foragers. DNA sequencing yielded a contig of 21.5 kb spanning the honeybee IP3K locus and a 3′ flanking gene similar to a transcription factor NFR-κ-B. The IP3K locus gives rise to three differentially...[Show more]
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|Source:||Molecular Brain Research|
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