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Geriatric psychiatry: is the jury still out on the cognitive effects of homocysteine and one-carbon metabolism?

Looi, Jeffrey; Sachdev, Perminder Singh


Purpose of review: This review considers the evidence for the contribution of hyperhomocysteinemia to cognitive impairment, the dementias and Parkinson's disease, focusing on published literature from April 2002 to April 2003. Recent findings: Homocysteine is a sulphur-containing amino acid that is involved in cycles related to one-carbon metabolism within the body, and elevations in its level can result from multiple aspects of these cycles. Elevated homocysteine impairs methylation, crucial...[Show more]

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
Source: Current Opinion In Psychiatry
DOI: 10.1097/00001504-200311000-00008


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