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Cyclodextrins to limit substrate inhibition and alter substrate selectivity displayed by enzymes

Easton, Christopher; Harper, Jason B; Head, Sarah; Lee, Kitty; Lincoln, Stephen F


The substrate inhibition exhibited by carboxypeptidase A in catalysing the hydrolysis of (S)-2-O-(N-benzoylglycyl)β-phenyllactate) is limited by addition of cyclodextrins. The cyclodextrins do not significantly change the maximum rate of reaction, but th

CollectionsANU Research Publications
Date published: 2001
Type: Journal article
Source: Journal of the Chemical Society, Perkin Transactions 1


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