The Ubp6 family of deubiquitinating enzymes contains a ubiquitin-like domain: SUb
Wyndham, A; Baker, Rohan; Chelvanayagam, Gareth
Description
A sequence motif that is similar to Ubiquitin (SUb) has been identified in the Saccharomyces cerevisiae ubiquitin-specific protease Ubp6. SUb is conserved in all known Ubp6 homologues from a spectrum of eukaryotic species and is also present in a group of hypothetical proteins of unknown function (Unk1-3) present in sequence databases. An N-terminal deletion mutant of Ubp6 that lacks SUb is still capable of cleaving α-linked ubiquitin fusions, suggesting that SUb forms a separate domain to the...[Show more]
Collections | ANU Research Publications |
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Date published: | 1999 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/92534 |
Source: | Protein Science |
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File | Description | Size | Format | Image |
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01_Wyndham_The_Ubp6_family_of_1999.pdf | 558.75 kB | Adobe PDF | Request a copy |
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