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Gene structure, expression and chromosomal localization of murine theta class glutathione transferase mGSTT1-1

Whittington, A; Vichai, Vanicha; Webb, G; Baker, Rohan; Pearson, William R; Board, Philip

Description

We have isolated and characterized a cDNA and partial gene encoding a murine subfamily 1 Theta class glutathione transferase (GST). The cDNA derived from mouse GSTT1 has an open reading frame of 720 bp encoding a peptide of 240 amino acids with a calculated molecular mass of 27356 Da. The encoded protein shares only 51% deduced amino acid sequence identity with mouse GSTT2, but greater than 80% deduced amino acid sequence identity with rat GSTT1 and human GSTT1. Mouse GSTT1-1 was expressed in...[Show more]

CollectionsANU Research Publications
Date published: 1999
Type: Journal article
URI: http://hdl.handle.net/1885/92533
Source: Biochemical Journal
DOI: 10.1042/0264-6021:3370141

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