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Glutathione transferase zeta-catalyzed biotransformation of deuterated dihaloacetic acids

Werkmeister, Jerome A; Anderson, Warwick P; Tzeng, Huey-Fen; Board, Philip; Anders, Michael

Description

Glutathione transferase zeta (GSTZ) catalyzes the biotransformation of α-haloalkanoic acids. Treatment of rats or humans with dichloroacetic acid prolongs its elimination half-life, and preliminary studies in this laboratory show that fluorine-lacking, b

CollectionsANU Research Publications
Date published: 1999
Type: Journal article
URI: http://hdl.handle.net/1885/92532
Source: Biochemical and Biophysical Research Communications
DOI: 10.1006/bbrc.1999.1127

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