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Characterization and chromosomal localization of USP3, a novel human ubiquitin-specific protease

Sloper-Mould, K; Eyre, Helen; Wang, Xiao Wen; Sutherland, Grant; Baker, Rohan

Description

Conjugation to the small eukaryotic protein ubiquitin can functionally modify or target proteins for degradation by the proteasome. Removal of the ubiquitin modification, or deubiquitination, is performed by ubiquitin- specific proteases and is an important mechanism regulating this pathway. Here we describe a novel human ubiquitin-specific protease, USP3, initially identified as a partial cDNA clone similar to one of two highly conserved sequence regions common to all ubiquitin-specific...[Show more]

CollectionsANU Research Publications
Date published: 1999
Type: Journal article
URI: http://hdl.handle.net/1885/92530
Source: Biological Chemistry
DOI: 10.1074/jbc.274.38.26878

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