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A scan for linkage disequilibrium across the human genome

Huttley, Gavin Austin; Smith, M; Carrington, M; O'Brien, Patricia C M


Linkage disequilibrium (LD), the tendency for alleles of linked loci to co-occur nonrandomly on chromosomal haplotypes, is an increasingly useful phenomenon for (1) revealing historic perturbation of populations including founder effects, admixture, or incomplete selective sweeps; (2) estimating elapsed time since such events based on time-dependent decay of LD; and (3) disease and phenotype mapping, particularly for traits not amenable to traditional pedigree analysis. Because few descriptions...[Show more]

CollectionsANU Research Publications
Date published: 1999
Type: Journal article
Source: Genetics (Print) ceased Dec 2009 - don't use


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