A region between -141 and -61 bp containing a proximal AP-1 is essential for constitutive expression of urokinase-type plasminogen activator receptor
An 8.5-kb 5'-flanking region of the human urokinase-type plasminogen activator receptor (uPAR) gene was cloned and the detailed uPAR promoter region defined in an 188-bp fragment between bases -141 and +47 relative to the transcription-start site. 5;-Deletion to - 100 and -60 in the region abolished its promoter activity, indicating that an 81-bp segment between - 141 and -61, which contains a proximal AP-1 site at position -70, is required for uPAR promoter activity. Nuclear extracts from...[Show more]
|Collections||ANU Research Publications|
|Source:||European Journal of Biochemistry|
|01_Dang_A_region_between_-141_and_-61_1999.pdf||676.79 kB||Adobe PDF||Request a copy|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.