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Chloramphenicol-Induced Amnesia for Passive Avoidance Training in the Day-Old Chick

Freeman, Fiona; Young, I M


The antibiotic chloramphenicol, an inhibitor of mitochondrial protein synthesis, was used to investigate the time-related changes in protein synthesis following passive avoidance training in the day-old chick (white leghorn-black Australorp). Retention of memory for this simple learning task is known to be prevented by an inhibitor of cytosolic protein synthesis, anisomycin, in a biphasic manner, with the first phase of sensitivity occurring up to 90 min post-training and the second phase...[Show more]

CollectionsANU Research Publications
Date published: 1999
Type: Journal article
Source: Neurobiology of Learning and Memory
DOI: 10.1006/nlme.1998.3867


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