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Biochemical and Functional Characterization of Human Transmembrane Tryptase(TMT)Ttryptase g.

Wong, Guang; Foster, Paul S; Yasuda, Shinsuke; Qi, Jian; Mahalingam, Surendran; Mellor, Elizabeth; Katsoulotos, Gregory; Li, Lixin; Boyce, Joshua; Krilis, Steven; Stevens, Richard

Description

Transmembrane tryptase (TMT)/tryptase γ is a membrane-bound serine protease stored in the secretory granules of human and mouse lung mast cells (MCs). We now show that TMT reaches the external face of the plasma membrane when MCs are induced to degranula

dc.contributor.authorWong, Guang
dc.contributor.authorFoster, Paul S
dc.contributor.authorYasuda, Shinsuke
dc.contributor.authorQi, Jian
dc.contributor.authorMahalingam, Surendran
dc.contributor.authorMellor, Elizabeth
dc.contributor.authorKatsoulotos, Gregory
dc.contributor.authorLi, Lixin
dc.contributor.authorBoyce, Joshua
dc.contributor.authorKrilis, Steven
dc.contributor.authorStevens, Richard
dc.date.accessioned2015-12-13T23:24:24Z
dc.identifier.issn0021-9258
dc.identifier.urihttp://hdl.handle.net/1885/92208
dc.description.abstractTransmembrane tryptase (TMT)/tryptase γ is a membrane-bound serine protease stored in the secretory granules of human and mouse lung mast cells (MCs). We now show that TMT reaches the external face of the plasma membrane when MCs are induced to degranula
dc.publisherAmerican Society for Biochemistry and Molecular Biology Inc
dc.sourceJournal of Biological Chemistry
dc.subjectKeywords: Amino acids; Biological membranes; Cells; Genes; Genetic engineering; Living systems studies; RNA; Signal transducers; Enzymes; alpha 1 antitrypsin; interleukin 13 receptor; interleukin 4 receptor; STAT6 protein; transmembrane tryptase; tryptase; tryptase
dc.titleBiochemical and Functional Characterization of Human Transmembrane Tryptase(TMT)Ttryptase g.
dc.typeJournal article
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.citationvolume277
dc.date.issued2002
local.identifier.absfor030499 - Medicinal and Biomolecular Chemistry not elsewhere classified
local.identifier.ariespublicationMigratedxPub23226
local.type.statusPublished Version
local.contributor.affiliationWong, Guang, Harvard Medical School
local.contributor.affiliationFoster, Paul S, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationYasuda, Shinsuke, Harvard Medical School
local.contributor.affiliationQi, Jian, University of New South Wales
local.contributor.affiliationMahalingam, Surendran, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationMellor, Elizabeth, Harvard Medical School
local.contributor.affiliationKatsoulotos, Gregory, University of New South Wales
local.contributor.affiliationLi, Lixin, Harvard University
local.contributor.affiliationBoyce, Joshua, Harvard University
local.contributor.affiliationKrilis, Steven, University of New South Wales
local.contributor.affiliationStevens, Richard, Harvard University
local.description.embargo2037-12-31
local.bibliographicCitation.issue44
local.bibliographicCitation.startpage41906
local.bibliographicCitation.lastpage41915
local.identifier.doi10.1074/jbc.M205868200
dc.date.updated2015-12-12T09:20:21Z
local.identifier.scopusID2-s2.0-0036830570
CollectionsANU Research Publications

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