A randomized controlled trial of buprenorphine in the management of short-term ambulatory heroin withdrawal
Aim: To determine whether buprenorphine is more effective than clonidine and other symptomatic medications in managing ambulatory heroin withdrawal. Design: Open label, prospective randomized controlled trial examining withdrawal and 4-week postwithdrawal outcomes on intention-to-treat. Setting: Two specialist, out-patient drug treatment centres in inner city Melbourne and Sydney, Australia. Participants: One hundred and fourteen dependent heroin users were recruited. Participants were 18 years...[Show more]
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