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Passive Ca2+ Transport and Ca2-dependent K+ transport in Plasmodium falciparum-infected red cells

Staines, Henry M; Chang, W; Ellory, J Clive; Tiffert, Teresa; Kirk, Kiaran; Lew, Vergilio


Previous reports have indicated that Plasmodium falciparum-infected red cells (pRBC) have an increased Ca2+ permeability. The magnitude of the increase is greater than that normally required to activate the Ca2+- dependent K+ channel (K(Ca) channel) of the red cell membrane. However, there is evidence that this channel remains inactive in pRBC. To clarify this discrepancy, we have reassessed both the functional status of the K(Ca) channel and the Ca2+ permeability properties of pRBC. For pRBC...[Show more]

CollectionsANU Research Publications
Date published: 1999
Type: Journal article
Source: Journal of Membrane Biology
DOI: 10.1007/s002329900579


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