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Spleen stromal cells support haemopoiesis and in vitro growth of dendritic cells from bone marrow

Ni, Keping; O'Neill, Helen


Long-term stroma-dependent cultures from murine spleen have been previously shown to support dendritic cell (DC) development in vitro. Secondary cultures have now been established using a splenic stromal cell layer overlaid with cells from different lymphoid sites. Cells resembling DCs can be generated in vitro from unfractionated murine lymphoid cells in the absence of added growth factors. Bone marrow (BM) cultures are the most successful but some cultures have been derived from spleen and...[Show more]

CollectionsANU Research Publications
Date published: 2000
Type: Journal article
Source: British Journal of Haematology
DOI: 10.1111/j.1365-2141.1999.01294.x


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