Hill, Caryl; Eade, Joyce; Sandow, Shaun L
1. Mechanisms underlying spontaneous rhythmical contractions have been studied in irideal arterioles of the rat using video microscopy and electrophysiology. 2. Rhythmical contractions (4 min-1) were more common during the second and third postnatal weeks and were always preceded by large, slow depolarizations (5-40 mV). 3. Spontaneous contractions were unaffected by tetrodotoxin (1 μM), neurotransmitter receptor antagonists, the sympathetic neurone blocker, guanethidine (5 μM) or sensory...[Show more]
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