Mechanisms underlying spontaneous rhythmical contractions in irideal arterioles of the rat
1. Mechanisms underlying spontaneous rhythmical contractions have been studied in irideal arterioles of the rat using video microscopy and electrophysiology. 2. Rhythmical contractions (4 min-1) were more common during the second and third postnatal weeks and were always preceded by large, slow depolarizations (5-40 mV). 3. Spontaneous contractions were unaffected by tetrodotoxin (1 μM), neurotransmitter receptor antagonists, the sympathetic neurone blocker, guanethidine (5 μM) or sensory...[Show more]
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|Source:||Journal of Physiology|
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