Analysis of B cell memory formation using DNA microarrays
DNA microarray analysis of B cell subsets has identified comprehensive programs of gene expression that distinguish B cells at discrete stages of differentiation. The next task is to identify key genetic signals within these complex programs that regulate the dynamic cellular events during B cell activation in vivo. After stimulation with antigen, naïve B cells proliferate and differentiate, and then produce antibodies. Crucial qualitative differences in antibody responses are observed...[Show more]
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|Source:||Annals of the New York Academy of Sciences|
|01_Garcia De Vinuesa_Analysis_of_B_cell_memory_2002.pdf||2.07 MB||Adobe PDF||Request a copy|
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