Hydrolysis of the 5'- p -Nitrophenyl Ester of TMP by the Proofreading Exonuclease (ε) Subunit of Escherichia coli DNA Polymerase III
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Hamdan, Samir; Bulloch, Esther; Thompson, Phillip; Beck, Jennifer; Yang, Ji Yeon; Crowther, Jeffrey; Lilley, Penelope; Carr, Paul D; Ollis, David; Brown, Susan Elizabeth; Dixon, Nicholas
Description
The core of DNA polymerase III, the replicative polymerase in Escherichia coli, consists of three subunits (α, ε, and θ). The ε subunit is the 3′-5′ proofreading exonuclease that associates with the polymerase (α) through its C-terminal region an
dc.contributor.author | Hamdan, Samir | |
---|---|---|
dc.contributor.author | Bulloch, Esther | |
dc.contributor.author | Thompson, Phillip | |
dc.contributor.author | Beck, Jennifer | |
dc.contributor.author | Yang, Ji Yeon | |
dc.contributor.author | Crowther, Jeffrey | |
dc.contributor.author | Lilley, Penelope | |
dc.contributor.author | Carr, Paul D | |
dc.contributor.author | Ollis, David | |
dc.contributor.author | Brown, Susan Elizabeth | |
dc.contributor.author | Dixon, Nicholas | |
dc.date.accessioned | 2015-12-13T23:22:26Z | |
dc.identifier.issn | 0006-2960 | |
dc.identifier.uri | http://hdl.handle.net/1885/91445 | |
dc.description.abstract | The core of DNA polymerase III, the replicative polymerase in Escherichia coli, consists of three subunits (α, ε, and θ). The ε subunit is the 3′-5′ proofreading exonuclease that associates with the polymerase (α) through its C-terminal region an | |
dc.publisher | American Chemical Society | |
dc.source | Biochemistry | |
dc.subject | Keywords: 4 nitrophenyl 3' thymidylate; 4-nitrophenyl 3'-thymidylate; divalent cation; DNA directed DNA polymerase gamma; drug derivative; exodeoxyribonuclease; exodeoxyribonuclease V; magnesium; manganese; thymidine phosphate; ester derivative; exonuclease; magnes | |
dc.title | Hydrolysis of the 5'- p -Nitrophenyl Ester of TMP by the Proofreading Exonuclease (ε) Subunit of Escherichia coli DNA Polymerase III | |
dc.type | Journal article | |
local.description.notes | Imported from ARIES | |
local.description.refereed | Yes | |
local.identifier.citationvolume | 41 | |
dc.date.issued | 2002 | |
local.identifier.absfor | 030499 - Medicinal and Biomolecular Chemistry not elsewhere classified | |
local.identifier.ariespublication | MigratedxPub22200 | |
local.type.status | Published Version | |
local.contributor.affiliation | Hamdan, Samir, College of Physical and Mathematical Sciences, ANU | |
local.contributor.affiliation | Bulloch, Esther, College of Physical and Mathematical Sciences, ANU | |
local.contributor.affiliation | Thompson, Phillip, College of Physical and Mathematical Sciences, ANU | |
local.contributor.affiliation | Beck, Jennifer, College of Physical and Mathematical Sciences, ANU | |
local.contributor.affiliation | Yang, Ji Yeon, College of Physical and Mathematical Sciences, ANU | |
local.contributor.affiliation | Crowther, Jeffrey, College of Physical and Mathematical Sciences, ANU | |
local.contributor.affiliation | Lilley, Penelope, College of Physical and Mathematical Sciences, ANU | |
local.contributor.affiliation | Carr, Paul D, College of Physical and Mathematical Sciences, ANU | |
local.contributor.affiliation | Ollis, David, College of Physical and Mathematical Sciences, ANU | |
local.contributor.affiliation | Brown, Susan Elizabeth, College of Physical and Mathematical Sciences, ANU | |
local.contributor.affiliation | Dixon, Nicholas, College of Physical and Mathematical Sciences, ANU | |
local.description.embargo | 2037-12-31 | |
local.bibliographicCitation.issue | 16 | |
local.bibliographicCitation.startpage | 5266 | |
local.bibliographicCitation.lastpage | 5275 | |
local.identifier.doi | 10.1021/bi0159480 | |
dc.date.updated | 2015-12-12T09:11:00Z | |
local.identifier.scopusID | 2-s2.0-0037161144 | |
Collections | ANU Research Publications |
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