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Hydrolysis of the 5'- p -Nitrophenyl Ester of TMP by the Proofreading Exonuclease (ε) Subunit of Escherichia coli DNA Polymerase III

Hamdan, Samir; Bulloch, Esther; Thompson, Phillip; Beck, Jennifer; Yang, Ji Yeon; Crowther, Jeffrey; Lilley, Penelope; Carr, Paul D; Ollis, David; Brown, Susan Elizabeth; Dixon, Nicholas


The core of DNA polymerase III, the replicative polymerase in Escherichia coli, consists of three subunits (α, ε, and θ). The ε subunit is the 3′-5′ proofreading exonuclease that associates with the polymerase (α) through its C-terminal region an

CollectionsANU Research Publications
Date published: 2002
Type: Journal article
Source: Biochemistry
DOI: 10.1021/bi0159480


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