Skip navigation
Skip navigation

Molecular dynamics estimates of ion diffusion in model hydrophobic and KcsA potassium channels

Allen, Toby; Kuyucak, Serdar; Chung, Shin-Ho

Description

Molecular dynamics simulations are carried out to obtain estimates of diffusion coefficients of biologically important Na+, K+, Ca2+ and Cl- ions in hydrophobic cylindrical channels with varying radii and large reservoirs. Calculations for the cylindrical channels are compared to those for the KcsA potassium channel, for which the protein structure has recently been determined from X-ray diffraction experiments. Our results show that ion diffusion is maintained at reasonably high levels even...[Show more]

CollectionsANU Research Publications
Date published: 2000
Type: Journal article
URI: http://hdl.handle.net/1885/91192
Source: Biophysical Chemistry
DOI: 10.1016/S0301-4622(00)00153-8

Download

File Description SizeFormat Image
01_Allen_Molecular_dynamics_estimates_2000.pdf193.77 kBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator