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IMMUNOHISTOCHEMICAL LOCALIZATION AND ACTIVITY OF GLUTATHIONE TRANSFERASE ZETA (GSTZ1-1) IN RAT TISSUES

Lantum, Hoffman; Baggs, Raymond; Krenitsky, Daria; Board, Philip; Anders, Michael

Description

Glutathione transferase zeta (GSTZ1-1) catalyzes the biotransformation of a range of α-haloacids, including dichloroacetic acid (DCA), and the penultimate step in the tyrosine degradation pathway. DCA is a rodent carcinogen and a common drinking water co

CollectionsANU Research Publications
Date published: 2002
Type: Journal article
URI: http://hdl.handle.net/1885/91063
Source: Drug Metabolism and Disposition
DOI: 10.1124/dmd.30.6.616

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