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Prognostic significance of extensive microsatellite instability in sporadic clinicopathological stage C colorectal cancer

Wright, Crispin; Dent, Owen; Barker, M; Newland, R; Chapuis, P; Bokey, E; Young, J P; Leggett, B; Jass, Jeremy; Macdonald, Graham J


Background: Colorectal cancers exhibiting microsatellite instability (MSI) appear to have unique biological behaviour. This study analyses the association between extensive MSI (MSI-H), clinicopathological features and survival in an unselected group of patients with sporadic Australian Clinico-Pathological Stage (ACPS) C (tumour node metastasis stage III) colorectal cancer. Methods: Some 255 patients who underwent resection for sporadic ACPS C colorectal cancer between 1986 and 1992 were...[Show more]

CollectionsANU Research Publications
Date published: 2000
Type: Journal article
Source: British Journal of Surgery
DOI: 10.1046/j.1365-2168.2000.01508.x


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