Prognostic significance of extensive microsatellite instability in sporadic clinicopathological stage C colorectal cancer
Background: Colorectal cancers exhibiting microsatellite instability (MSI) appear to have unique biological behaviour. This study analyses the association between extensive MSI (MSI-H), clinicopathological features and survival in an unselected group of patients with sporadic Australian Clinico-Pathological Stage (ACPS) C (tumour node metastasis stage III) colorectal cancer. Methods: Some 255 patients who underwent resection for sporadic ACPS C colorectal cancer between 1986 and 1992 were...[Show more]
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|Source:||British Journal of Surgery|
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