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TrExML: a maximum-likelihood approach for extensive tree-space exploration

Wolf, Marty; Easteal, Simon; Kahn, Margaret; McKay, Brendan; Jermiin, Lars

Description

Motivation: Maximum-likelihood analysis of nucleotide and amino acid sequences is a powerful approach for inferring phylogenetic relationships and for comparing evolutionary hypotheses. Because it is a computationally demanding and time-consuming process, most algorithms explore only a minute portion of tree-space, with the emphasis on finding the most likely tree while ignoring the less likely, but not significantly worse, trees. However when such trees exist, it is equally important to...[Show more]

CollectionsANU Research Publications
Date published: 2000
Type: Journal article
URI: http://hdl.handle.net/1885/90877
Source: Bioinformatics

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