Alpha class glutathione transferase polymorphisms identified by EST database analysis
Tetlow, Natasha; Blackburn, Anneke; Chelvanayagam, Gareth; Board, Philip
Description
Polymorphisms in the mu, pi and theta class glutathione transferase (GST) genes have been implicated in susceptibility to a number of diseases. New polymorphisms can be identified by searching the expressed sequence tag (EST) database, as it contains a multitude of sequences collected from many individuals. The EST database was used to search for polymorphisms in the GST alpha class genes. The presence of confirmed polymorphisms in three different ethnic groups has been examined, and the...[Show more]
dc.contributor.author | Tetlow, Natasha | |
---|---|---|
dc.contributor.author | Blackburn, Anneke | |
dc.contributor.author | Chelvanayagam, Gareth | |
dc.contributor.author | Board, Philip | |
dc.date.accessioned | 2015-12-13T23:20:31Z | |
dc.date.available | 2015-12-13T23:20:31Z | |
dc.identifier.issn | 0009-2797 | |
dc.identifier.uri | http://hdl.handle.net/1885/90743 | |
dc.description.abstract | Polymorphisms in the mu, pi and theta class glutathione transferase (GST) genes have been implicated in susceptibility to a number of diseases. New polymorphisms can be identified by searching the expressed sequence tag (EST) database, as it contains a multitude of sequences collected from many individuals. The EST database was used to search for polymorphisms in the GST alpha class genes. The presence of confirmed polymorphisms in three different ethnic groups has been examined, and the recombinant proteins expressed in Escherichia coli for further study. | |
dc.publisher | Elsevier | |
dc.source | Chemico-Biological Interactions | |
dc.subject | Keywords: Database analysis; EST database; Glutathione transferase; Polymorphism | |
dc.title | Alpha class glutathione transferase polymorphisms identified by EST database analysis | |
dc.type | Journal article | |
local.description.notes | Imported from ARIES | |
local.description.refereed | Yes | |
local.identifier.citationvolume | 133 | |
dc.date.issued | 2001 | |
local.identifier.absfor | 060107 - Enzymes | |
local.identifier.ariespublication | MigratedxPub21184 | |
local.type.status | Published Version | |
local.contributor.affiliation | Tetlow, Natasha, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Blackburn, Anneke, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Chelvanayagam, Gareth, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Board, Philip, College of Medicine, Biology and Environment, ANU | |
local.bibliographicCitation.startpage | 123 | |
local.bibliographicCitation.lastpage | 125 | |
dc.date.updated | 2015-12-12T09:03:27Z | |
local.identifier.scopusID | 2-s2.0-0003205233 | |
Collections | ANU Research Publications |
Download
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.
Updated: 17 November 2022/ Responsible Officer: University Librarian/ Page Contact: Library Systems & Web Coordinator