Skip navigation
Skip navigation

Polyunsaturated nitroalkanes and nitro-substituted fatty acids

Easton, Christopher; Xia, Ling; Pitt, Michael; Ferrante, Antonio; Poulos, Alf; Rathjen, Deborah A


Nitroalkanes 4 are readily prepared from naturally derived polyunsaturated fatty alcohols 1 via succesive conversion to the corresponding haloalkanes 2 and 3, and reaction with silver nitrite. Reaction of nitroalkanes 4a,b with methyl acrylate, followed by ester hydrolysis, affords nitro-substituted fatty acids 6a,b and 8a,b. Oxidation of alcohols 1a,b gives the corresponding aldehydes 9a,b, which react by Henry condensation with nitromethane to give β-hydroxynitroalkanes 10a,b.

CollectionsANU Research Publications
Date published: 2001
Type: Journal article
Source: Synthesis


There are no files associated with this item.

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator