Skip navigation
Skip navigation

Characterization of the Omega class glutathione transferases

Board, Philip; Coggan, Marjorie; Chelvanayagam, Gareth; Easteal, Simon; Jermiin, Lars Sommer; Schulte, Jurgen; Danley, D; Hoth, L; Griffor, M; Kamath, A; Rosner, M; Chrunyk, B; Perregaux, D; Gabel, C; Gatens, Moira; Pandit, J

Description

The Omega class of glutathione transferases (GST) has been discovered by analysis of the expressed sequence tag database and sequence alignment. In humans, GSTO 1-1 is expressed in most tissues and exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities characteristic of the glutaredoxins. The crystal structure indicates that GSTO 1-1 has a characteristic GST fold. Unlike other mammalian glutathione transferases, GSTO 1-1 appears to have an active site...[Show more]

CollectionsANU Research Publications
Date published: 2001
Type: Journal article
URI: http://hdl.handle.net/1885/90731
Source: Chemico-Biological Interactions

Download

There are no files associated with this item.


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator