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Oxidation of oxa and thia fatty acids and related compounds catalyzed by 5- and 15-lipoxygenase

Easton, Christopher; Robertson, Thomas; Pitt, Michael; Rathjen, Deborah A; Ferrante, Antonio; Poulos, Alf


The modified fatty acids, (Z,Z,Z)-(octadeca-6,9,12-trienyloxy)acetic acid, (Z,Z,Z)-(octadeca-9,12,15-trienyloxy)acetic acid, (all-Z)-(eicosa-5,8,11,14-tetraenyloxy)acetic acid, (all-Z)-(eicosa-5,8,11,14-tetraenylthio)acetic acid, 3-[(all-Z)-(eicosa-5,8,11,14-tetraenylthio)]propionic acid, (all-Z)-(eicosa-5,8,11,14-tetraenylthio)succinic acid, N-[(all-Z)-(eicosa-5,8,11,14-tetraenoyl)]glycine and N-[(all-Z)-(eicosa-5,8,11,14-tetraenoyl)]aspartic acid, all react with soybean 15-lipoxygenase. The...[Show more]

CollectionsANU Research Publications
Date published: 2001
Type: Journal article
Source: Bioorganic and Medicinal Chemistry
DOI: 10.1016/S0968-0896(00)00246-7


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