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Functional analysis of the O antigen glucosylation gene cluster of Shegella Flexneri bacteriophage SfX

Guan, S; Bastin, David A; Verma, Naresh


Previous studies have shown that Shigella flexneri bacteriophage X (SfX) encodes a glucosyltransferase (GtrX, formerly Gtr), which is involved in O antigen modification (serotype Y to serotype X). However, GtrX alone can only mediate a partial conversion. More recently, a three-gene cluster has been identified next to the attachment site in the genome of two other S. flexneri bacteriophages (i.e. SfV and SfII). This gene cluster was postulated to be responsible for a full O antigen conversion....[Show more]

CollectionsANU Research Publications
Date published: 1999
Type: Journal article
Source: Microbiology (Russia)


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