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Mechanisms of prion-induced modifications in membrane transport properties: Implications for signal transduction and neurotoxicity

Kourie, Joseph

Description

Prion-related encephalopathies are associated with the conversion of a normal cellular isoform of prion protein (PrPc) to an abnormal pathologic scrapie isoform (PrPSc). The conversion of this single polypeptide chain involves a reduction in the α-helice

CollectionsANU Research Publications
Date published: 2001
Type: Journal article
URI: http://hdl.handle.net/1885/90564
Source: Chemico-Biological Interactions
DOI: 10.1016/S0009-2797(01)00228-9

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