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Membrane properties and spike generation in rat visual cortical cells during reversible cooling

Volgushev, M; Vidyasagar, T R; Chistiakova, Marina; Yousef, Tagrid; Eysel, Ulf


1. We studied the effects of reversible cooling between 35 and 7 C on membrane properties and spike generation of cells in slices of rat visual cortex. 2. Cooling led to a depolarization of the neurones and an increase of the input resistance, thus bringing the cells closer to spiking threshold. Excitability, measured with intracellular current steps, increased with cooling. 3. Synaptic stimuli were most efficient in producing spikes at room temperature, but strong stimulation could evoke...[Show more]

CollectionsANU Research Publications
Date published: 2000
Type: Journal article
Source: Journal of Physiology


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