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Database Analysis and Gene Discovery in Parmacogenetics

Board, Philip; Tetlow, Natasha; Blackburn, Anneke; Chelvanayagam, Gareth


The global genome research effort has resulted in the creation of extensive DNA and protein sequence data-bases that are a valuable resource for the identification of new genes and polymorphic variants of enzymes of pharmacogenetic interest. Previously undescribed members of gene families with novel functions and substrate specificities can be identified by database searching and sequence alignment strategies. Since the expressed sequence tag (EST) database contains sequences from many...[Show more]

CollectionsANU Research Publications
Date published: 2000
Type: Journal article
Source: Clinical Chemistry and Laboratory Medicine


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