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Cytokines in innate and adaptive immunity

Banyer, Joanne; Hamilton, Nicholas H R; Ramshaw, Ian; Ramsay, R

Description

Cytokines and chemokines are hormone-like messengers which act to regulate the development and expression of the broad array of immune responses that are mounted against a variety of pathogens. As such, they are critical determinants of the types of cells which will regulate and participate in innate and adaptive immune responses, they may act both in highly localised environments but also in a systemic manner, and they may, themselves, directly mediate antimicrobial effector activities. In...[Show more]

dc.contributor.authorBanyer, Joanne
dc.contributor.authorHamilton, Nicholas H R
dc.contributor.authorRamshaw, Ian
dc.contributor.authorRamsay, R
dc.date.accessioned2015-12-13T23:18:49Z
dc.date.available2015-12-13T23:18:49Z
dc.identifier.issn1398-1714
dc.identifier.urihttp://hdl.handle.net/1885/90361
dc.description.abstractCytokines and chemokines are hormone-like messengers which act to regulate the development and expression of the broad array of immune responses that are mounted against a variety of pathogens. As such, they are critical determinants of the types of cells which will regulate and participate in innate and adaptive immune responses, they may act both in highly localised environments but also in a systemic manner, and they may, themselves, directly mediate antimicrobial effector activities. In this article, we will outline current concepts of the activities of cytokines and chemokines in the immune response and discuss the various cell types, including dendritic cells and other antigen-presenting cells, T cells and B cells, which both produce and respond to these potent regulatory molecules.
dc.publisherMunksgaard International Publishers
dc.sourceReviews in Immunogenetics
dc.subjectKeywords: chemokine; cytokine; gamma interferon; glycoprotein gp 39; interleukin 12; interleukin 1alpha; interleukin 2; interleukin 4; interleukin 5; interleukin 6; interleukin 7; tumor necrosis factor alpha; adaptation; antimicrobial activity; B lymphocyte; cytoki Adaptive immunity; Chemokine; Cytokine; Dendritic cells; Innate immunity
dc.titleCytokines in innate and adaptive immunity
dc.typeJournal article
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.citationvolume2
dc.date.issued2000
local.identifier.absfor110104 - Medical Biochemistry: Lipids
local.identifier.ariespublicationMigratedxPub20701
local.type.statusPublished Version
local.contributor.affiliationBanyer, Joanne, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationHamilton, Nicholas H R, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationRamshaw, Ian, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationRamsay, R, Louisiana State University
local.bibliographicCitation.startpage359
local.bibliographicCitation.lastpage373
dc.date.updated2015-12-12T08:58:21Z
local.identifier.scopusID2-s2.0-0034526275
CollectionsANU Research Publications

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