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The flightless I protein localizes to actin-based structures during embryonic development

Davy, Deborah; Ball, Eldon; Matthaei, Klaus; Campbell, Hugh; Crouch, Michael F

Description

The product of the flightless I gene is predicted to provide a link between molecules of an as yet unidentified signal transduction pathway and the actin cytoskeleton. Previous work has shown that weak and severe mutations of the flightless I locus in Drosophila melanogaster cause disruption in the indirect flight muscles and in embryonic cellularization events, respectively, indicative of a regulatory role for the flightless I protein in cytoskeletal rearrangements. A C-terminal domain within...[Show more]

CollectionsANU Research Publications
Date published: 2000
Type: Journal article
URI: http://hdl.handle.net/1885/90225
Source: Immunology and Cell Biology
DOI: 10.1046/j.1440-1711.2000.00926.x

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