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Euplectin and Coneuplectin, New Naphthopyrones from the Lichen Flavoparmelia euplecta

Ernst-Russell, M; Chai, Christina; Wardlaw, Judith; Elix, John

Description

Two new naphthopyrones, euplectin (1) and coneuplectin (2), have been isolated 'from the lichen Flavoparmelia euplecta and their structures elucidated using multidimensional NMR spectroscopic methods, including highfield (600 MHz) gHMBC and gNOE experiments. Cytotoxicity of the more abundant naphthopyrone (1) against the murine P-815 mastocytoma cell line (IC50 ca. 1.67 μg/mL) has also been evaluated. These compounds are the first lichen metabolites known to contain indenone or indanone...[Show more]

CollectionsANU Research Publications
Date published: 2000
Type: Journal article
URI: http://hdl.handle.net/1885/89906
Source: Journal of Natural Products
DOI: 10.1021/np9903245

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