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The mitcochondrial benzodiazepine receptor and avoidance learning in the day-old chick

Freeman, Fiona; Young, I M


The specific mitochondrial benzodiazepine receptor (MBR) agonist, FGIN 1-27, and antagonist, PK 11195, were used to investigate whether this receptor was involved in passive avoidance memory formation in the day-old chick. PK 11195 at a concentration of 1-10 μM was found to be amnesic when injected directly into the lobus parolfactorius (LPO) 5 h after training (P<.01). Unilateral injections of PK 11195 further showed that memory was only disrupted with injections into the right hemisphere...[Show more]

CollectionsANU Research Publications
Date published: 2000
Type: Journal article
Source: Pharmacology Biochemistry and Behavior
DOI: 10.1016/S0091-3057(00)00373-7


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