The mitcochondrial benzodiazepine receptor and avoidance learning in the day-old chick
The specific mitochondrial benzodiazepine receptor (MBR) agonist, FGIN 1-27, and antagonist, PK 11195, were used to investigate whether this receptor was involved in passive avoidance memory formation in the day-old chick. PK 11195 at a concentration of 1-10 μM was found to be amnesic when injected directly into the lobus parolfactorius (LPO) 5 h after training (P<.01). Unilateral injections of PK 11195 further showed that memory was only disrupted with injections into the right hemisphere...[Show more]
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|Source:||Pharmacology Biochemistry and Behavior|
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