Nitric oxide synthase activity in adrenocorticotrophin-induced hypertension in the rat
1. The nitric oxide (NO) system has been implicated in the pathogenesis of various forms of experimental hypertension. We studied nitric oxide synthase (NOS) activity as a possible indicator of NO production in adrenocorticotrophin (ACTH)-induced hypertension in the rat. 2. Haemodynamic, metabolic and biochemical parameters were examined in sham (saline)- and ACTH (100 μg/kg per day)-treated male Sprague-Dawley rats (n = 20). 3. Adrenocorticotrophin treatment increased systolic blood pressure,...[Show more]
|Collections||ANU Research Publications|
|Source:||Clinical and Experimental Pharmacology and Physiology|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.