Skip navigation
Skip navigation

The role of corticosterone in corticotrophin (ACTH)-induced hypertension in the rat

Mangos, George; Turner, Steven; Fraser, Tafline; Whitworth, Judith


Objective: Corticotrophin (ACTH)-induced hypertension in the rat is prevented by L- but not D-arginine. We examined the effects of exogenous corticosterone in the male Sprague Dawley (SD) rat to determine whether ACTH-induced hypertension is mediated by corticosterone. Methods: Exogenous corticosterone (10, 20 or 40 mg/kg per day) or sham (polyethylene glycol (PEG) 1 ml/kg per day) was injected subcutaneously in divided doses (s/c b.d.) over 15 treatment days to 40 SD rats (n = 10 each group)....[Show more]

CollectionsANU Research Publications
Date published: 2000
Type: Journal article
Source: Journal of Hypertension


File Description SizeFormat Image
01_Mangos_The_role_of_corticosterone_in_2000.pdf195.24 kBAdobe PDF    Request a copy

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  17 November 2022/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator