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Pharmacological interference with glutamate re-uptake impairs long-term memory in the honeybee Apis mellifera

Maleszka, Ryszard; Helliwell, Paul; Kucharski, Robert


The role of glutamate in the central nervous system of invertebrates is poorly understood. In the present study we examined the effects of a glutamate transporter inhibitor, L-trans-2,4-pyrrolidine dicarboxylate (L-trans-2,4-PDC), on memory formation in the honeybee following a three-trial classical conditioning of the proboscis extension reflex (PER). Pre-training injections of the drug have no effect on acquisition and short-term (1 h) memory, but impair long-term (24 h), associative...[Show more]

CollectionsANU Research Publications
Date published: 2000
Type: Journal article
Source: Behavioural Brain Research
DOI: 10.1016/S0166-4328(00)00235-7


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