GABA mediates presynaptic inhibition at glycinergic synapses in a rat auditory brainstem nucleus
1. Many inhibitory nerve terminals in the mammalian anteroventral cochlear nucleus (AVCN) contain both glycine and GABA, but the reason for the co-localization of these two inhibitory neurotransmitters in the AVCN is unknown. We have investigated the roles of glycine and GABA at synapses on bushy cells in the rat AVCN, using receptor immunohistochemistry and electrophysiology. 2. Our immunohistochemical results show prominent punctate labelling of postsynaptic clusters of glycine receptors and...[Show more]
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|Source:||Journal of Physiology|
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