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The Application of Dendritic Cell-derived Exomes in Tumour Immunotherapy

Quah, Ben; O'Neill, Helen


Cancer arises from the aberrant proliferation of a single transformed cell. This population acquires the ability to metastasise. An effective way to remove cancer cells from the body is to activate tumour-specific cytotoxic T cells (CTL). Activation of naive T cells depends on the unique antigen presenting capacity of DC. Activated tumour antigen-specific CTL can destroy cancer cells without harm to normal tissue. Their ability to stimulate antigen specific T cell responses makes DC attractive...[Show more]

CollectionsANU Research Publications
Date published: 2000
Type: Journal article
Source: Cancer Biotherapy and Radiopharmaceuticals


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