Hill, Caryl; Hickey, Haruyo; Sandow, Shaun L
We have previously shown that myoendothelial gap junctions are more prevalent in distal than in proximal arteries of the rat mesentery. In the present study we have investigated the role of gap junctions in the mechanism of action of endothelium-derived hyperpolarizing factor (EDHF) in these same vessels following relaxation with acetylcholine. Arteries were pre- constricted with phenylephrine and concentration response curves to acetylcholine were constructed in the presence of...[Show more]
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