High-Mobility-Group Protein I Can Modulate Binding of Transcription Factors to the U5 Region of the Human Immunodificiency Virus Type 1 Proviral Promoter
HMG I/Y appears to be a multifunctional protein that relies on in its ability to interact with DNA in a structure-specific manner anti with DNA, binding transcriptional activators via distinct protein-protein interaction surfaces. To investigate the hypothesis that HMG I/Y may have a role in human immunodeficiency virus type 1 (HIV-1) expression, we have analyzed whether HMG I/Y interacts with the 5' long terminal repeat anti whether this interaction can modulate transcription factor binding....[Show more]
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|Source:||Journal of Virology|
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