It takes two transposons to tango: transposable-element-mediated chromosomal rearrangements.
Transposable elements (TEs) promote various chromosomal rearrangements more efficiently, and often more specifically, than other cellular processes1-3. One explanation of such events is homologous recombination between multiple copies of a TE present in a genome. Although this does occur, strong evidence from a number of TE systems in bacteria, plants and animals suggests that another mechanism - alternative transposition - induces a large proportion of TE-associated chromosomal rearrangements....[Show more]
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|Source:||Trends in Genetics|
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