Identification of active site residues of the pro-metastatic endoglycosidase heparanase

Hulett, Mark; Hornby, June; Ohms, Stephen J; Zuegg, J.; Freeman, Craig; Gready, Jill; Parish, Christopher

doi:10.1021/bi002080p

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Identification of active site residues of the pro-metastatic endoglycosidase heparanase

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Hulett, Mark; Hornby, June; Ohms, Stephen J; Zuegg, J.; Freeman, Craig; Gready, Jill; Parish, Christopher

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Heparanase is a β-D-endoglucuronidase that cleaves heparan sulfate (HS) and has been implicated in many important physiological and pathological processes, including tumor cell metastasis, angiogenesis, and leukocyte migration. We report herein the ident

Collections	ANU Research Publications
Date published:	2000
Type:	Journal article
URI:	http://hdl.handle.net/1885/88929
Source:	Biochemistry
DOI:	10.1021/bi002080p

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Identification of active site residues of the pro-metastatic endoglycosidase heparanase

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