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Diversity and Dynamics of Dendritic Signalling

Hausser, Michael; Spruston, Nelson; Stuart, Gregory J

Description

Communication between neurons in the brain occurs primarily through synapses made onto elaborate treelike structures called dendrites. New electrical and optical recording techniques have led to tremendous advances in our understanding of how dendrites contribute to neuronal computation in the mammalian brain. The varied morphology and electrical and chemical properties of dendrites enable a spectrum of local and long-range signaling, defining the input-output relationship of neurons and the...[Show more]

dc.contributor.authorHausser, Michael
dc.contributor.authorSpruston, Nelson
dc.contributor.authorStuart, Gregory J
dc.date.accessioned2015-12-13T23:15:27Z
dc.identifier.issn0036-8075
dc.identifier.urihttp://hdl.handle.net/1885/88900
dc.description.abstractCommunication between neurons in the brain occurs primarily through synapses made onto elaborate treelike structures called dendrites. New electrical and optical recording techniques have led to tremendous advances in our understanding of how dendrites contribute to neuronal computation in the mammalian brain. The varied morphology and electrical and chemical properties of dendrites enable a spectrum of local and long-range signaling, defining the input-output relationship of neurons and the rules for induction of synaptic plasticity. In this way, diversity in dendritic signaling allows individual neurons to carry out specialized functions within their respective networks.
dc.publisherAmerican Association for the Advancement of Science
dc.sourceScience
dc.subjectKeywords: action potential; cell structure; dendrite; human; human cell; nerve cell excitability; nerve cell network; nerve cell plasticity; priority journal; review; signal transduction; voltage clamp; Action Potentials; Animals; Brain; Calcium Signaling; Dendrite
dc.titleDiversity and Dynamics of Dendritic Signalling
dc.typeJournal article
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.citationvolume290
dc.date.issued2000
local.identifier.absfor110902 - Cellular Nervous System
local.identifier.ariespublicationMigratedxPub18765
local.type.statusPublished Version
local.contributor.affiliationHausser, Michael, University College London
local.contributor.affiliationSpruston, Nelson, Northwestern University
local.contributor.affiliationStuart, Gregory J, College of Medicine, Biology and Environment, ANU
local.description.embargo2037-12-31
local.bibliographicCitation.startpage737
local.bibliographicCitation.lastpage744
local.identifier.doi10.1126/science.290.5492.739
dc.date.updated2015-12-12T08:43:38Z
local.identifier.scopusID2-s2.0-0034721728
CollectionsANU Research Publications

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