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The Synthesis and Biological Evaluation of Two Analogues of the C -Riboside Showdomycin

Renner, Jens; Kruszelnicki, Irma; Adamiak, Beata; Willis, Anthony; Hammond, Edward; Su, Stephen; Burns, Christopher; Trybala, Edward; Ferro, Vito; Banwell, Martin

Description

Two novel analogues, 2 and 3, of the C-riboside showdomycin (1) have been prepared by exploiting the N-TIPS-substituted pyrrole 7 as a synthetic equivalent for the maleimide C3 anion. The tetraacetate precursor, 12, of target 2 as well as target 3 itself

dc.contributor.authorRenner, Jens
dc.contributor.authorKruszelnicki, Irma
dc.contributor.authorAdamiak, Beata
dc.contributor.authorWillis, Anthony
dc.contributor.authorHammond, Edward
dc.contributor.authorSu, Stephen
dc.contributor.authorBurns, Christopher
dc.contributor.authorTrybala, Edward
dc.contributor.authorFerro, Vito
dc.contributor.authorBanwell, Martin
dc.date.accessioned2015-12-13T23:14:43Z
dc.identifier.issn0004-9425
dc.identifier.urihttp://hdl.handle.net/1885/88750
dc.description.abstractTwo novel analogues, 2 and 3, of the C-riboside showdomycin (1) have been prepared by exploiting the N-TIPS-substituted pyrrole 7 as a synthetic equivalent for the maleimide C3 anion. The tetraacetate precursor, 12, of target 2 as well as target 3 itself
dc.publisherCSIRO Publishing
dc.sourceAustralian Journal of Chemistry
dc.subjectKeywords: Assays; Cells; Crystallography; Diffractometers; Diffusion; Dyes; Monolayers; Nitrogen compounds; Proteins; Solvents; Substitution reactions; Synthesis (chemical); X ray analysis; Anti-viral effects; C-nucleosides; C-riboside showdomycin; Flash chromatogr
dc.titleThe Synthesis and Biological Evaluation of Two Analogues of the C -Riboside Showdomycin
dc.typeJournal article
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.citationvolume58
dc.date.issued2005
local.identifier.absfor030503 - Organic Chemical Synthesis
local.identifier.ariespublicationMigratedxPub18583
local.type.statusPublished Version
local.contributor.affiliationRenner, Jens, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationKruszelnicki, Irma, Cytopia Pty Ltd
local.contributor.affiliationAdamiak, Beata , Goteborg University
local.contributor.affiliationWillis, Anthony, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationHammond, Edward, Progen Industries Ltd
local.contributor.affiliationSu, Stephen, Cytopia Pty Ltd
local.contributor.affiliationBurns, Christopher, Cytopia Pty Ltd
local.contributor.affiliationTrybala, Edward, Goteborg University
local.contributor.affiliationFerro, Vito, Progen Industries Ltd
local.contributor.affiliationBanwell, Martin, College of Physical and Mathematical Sciences, ANU
local.description.embargo2037-12-31
local.bibliographicCitation.issue2
local.bibliographicCitation.startpage86
local.bibliographicCitation.lastpage93
local.identifier.doi10.1071/CH04273
dc.date.updated2015-12-12T08:40:05Z
local.identifier.scopusID2-s2.0-20044372506
CollectionsANU Research Publications

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